Introduction
Acute pancreatitis is a common clinical problem globally. Pancreatitis can be interstitial or necrotic. Interstitial pancreatitis can result in acute pancreatic fluid collections (PFCs). These collections are generally homogeneous, do not extend into the pancreatic parenchyma, and tend to resolve spontaneously without intervention. Pseudocysts are generally seen a few weeks after pancreatitis (up to 4 weeks). These generally develop a wall, which matures in up to 4 weeks and has no or minimal necrosis. These tend to resolve spontaneously as well without intervention and would need intervention if they are symptomatic with a mature wall. When fluid collections are seen in a setting of acute necrotizing pancreatitis, they are called acute necrotic collections and can be intra- or extrapancreatic and do not have a defined wall. Walled-off necrosis (WON) is seen in a setting of pancreatic necrosis and is a heterogeneous collection of fluid and necrotic material, and typically develops a wall in about 4 weeks from the onset of acute pancreatitis.
Endoscopic ultrasound (EUS) and drainage of fluid collections has become a cornerstone for the management of symptomatic/infected WON or pseudocysts.
In this article, Dr. Sundeep Lakhtakia, Interventional Endoscopist at the Asian Institute of Gastroenterology, Hyderabad, India, shares his expert advice on endoscopic drainage of these fluid collections.
Dos
Don’ts